产品货号:
Z19377
中文名称:
KIR2DL5A抗体
英文名称:
Anti-KIR2DL5A Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-KIR2DL5A Antibody |
指标别名 | KIR2DL5A;CD158F;CD158F1;KIR2DL5;KIR2DL5.1;KIR2DL5.3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | KIR2DL5A |
抗体来源 | Rabbit |
抗体类型 | IgG |
计算分子量 | 41KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | KI2LA antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | CD158f,also known as KIR2DL5,is a polymorphic 60kDa transmembrane glycoprotein with two Ig-like extracellular domains by which it recognize HLA class I molecules.Its long intracellular domain contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that upon extracellular ligand-mediated phosphorylation serve as docking sites for inhibitory phosphatases,which results in blocking natural cytotoxicity as well as antibody-dependent cytotoxicity of the particular NK cell,and its adhesion toward target cells.Together with other killer inhibitory receptors CD158f is important for immunological tolerance to discriminate between normal and abnormal cells.Besides NK cells it is expressed on a small population of cytotoxic T cells.Expression of CD158f alleles is highly variable in the population. |
Uniprot ID | Q8N109 |
基因名全称 | Killer cell immunoglobulin-like receptor 2DL5A |
蛋白名全称 | Killer cell immunoglobulin-like receptor 2DL5A |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
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